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BEFORE USING FLEXERIL :

Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

Do not take this medicine if you are also taking a monoamine oxidase inhibitor (MAOI).

Use of this medication is not recommended if you are also taking tramadol. If you are taking tramadol, be sure your doctor knows.

ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking droperidol or fluoxetine.

Before taking this medication, tell your doctor if you have urinary retention or narrow-angle glaucoma or increased intraocular pressure (pressure inside the eye).

Do not take cyclobenzaprine if you have recently (within the last 6 weeks) had a heart attack, have irregular heartbeats, have a heart block, have heart conduction disturbance, have congestive heart failure, or ·have hyperthyroidism that is not under control.

Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.

DIRECTIONS FOR USING FLEXERIL:

Follow the directions for using this medicine provided by your doctor. This medicine may be taken with food if it upsets your stomach. Store Flexeril at room temperature, away from heat and light. If you miss a dose of Flexeril and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

FLEXERIL CAUTIONS :

FLEXERIL may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine.

This medication will add to the effects of other depressants or alcohol. Ask your pharmacist if you have questions about which medicines are depressants.

If you experience dry mouth , use sugarless candy or gum, or melt bits of ice in your mouth. If dry mouth continues for more than 2 weeks, contact your dentist or doctor. Do not use this medicine longer than recommended by your doctor.

FOR WOMEN: It is unknown if this medication is excreted in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Do not stop taking cyclobenzaprine suddenly if you have been taking it regularly for more than 1 week. This may cause nausea, headache and general discomfort.

POSSIBLE SIDE EFFECTS OF FLEXERIL:

SIDE EFFECTS, that may go away during treatment, include drowsiness, dizziness, fatigue, blurred vision, dry mouth, or unpleasant taste. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

DRUG INTERACTIONS :

Do not take cyclobenzaprine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Many drugs can increase drowsiness associated with cyclobenzaprine: antihistamines such as brompheniramine (Dimetane, Bromfed, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), azatadine (Optimine), clemastine (Tavist), and many others, narcotics (pain killers) such as meperidine (Demerol), morphine (MS Contin, MSIR, others), propoxyphene (Darvon, Darvocet), hydrocodone (Lorcet, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), and codeine (Fiorinal, Fioricet, Tylenol #3, others, sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), and secobarbital (Seconal), phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), and trifluoperazine (Stelazine, antidepressants such as doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), phenelzine (Nardil), and tranylcypromine (Parnate).

The stomach medicine cimetidine (Tagamet, Tagamet HB) and pain relievers such as aspirin, ibuprofen (Motrin, Advil), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT, Oruvail), fenoprofen (Nalfon), flurbiprofen (Ansaid), naproxen (Aleve, Anaprox, Naprosyn), and nabumetone (Relafen) may all increase the pain-relieving effects of cyclobenzaprine. Use these drugs under the supervision of your doctor.

IF YOU TAKE TOO MUCH FLEXERIL:

If Flexeril overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include drowsiness, fast or irregular heartbeat, enlarged pupils, seizures, and loss of consciousness, dry, hot, flushed skin, hallucinations (seeing, hearing, or feeling things that are not there), increase or decrease in body temperature, troubled breathing, unexplained muscle stiffness; unusual nervousness or restlessness (severe); vomiting (occurring together with other symptoms of overdose)

ADDITIONAL INFORMATION ABOUT FLEXERIL:

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. Do not store this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.